The first DNA sequencing was performed by Sanger and co-workers in the 1970s, using a method based on the attenuation of the growing nucleotide chain with dideoxythymidine triphosphate (ddTTP). The ...

In a way, sequencing DNA is very simple: There's a molecule, you look at it, and you write down what you find. You'd think it would be easy—and, for any one letter in the sequence, it is. The problem ...

Nanopore sensors are tiny devices used to detect and analyze individual molecules by measuring ionic changes as the molecules pass through nanometer-scale openings. These sensors are classified into ...

Antibiotic resistance is often framed as a hospital problem, but a growing body of evidence shows that the environment plays ...

By cleverly combining new techniques for analysing DNA at the level of individual molecules, we can achieve real breakthroughs in research into ...

PacBio has announced plans to enhance its methylation detection capabilities in HiFi sequencing by licensing advanced methods from Professor Dennis Lo and his team at The Chinese University of Hong ...

Hospital for Sick Children in Toronto researchers are reporting that targeted RNA sequencing can detect clinically actionable alterations in 87% of tumors and provide decisive findings where DNA-seq ...

New research suggests the mysterious Roman-era “Beachy Head Woman” was likely from Britain, not the Mediterranean or ...